Virion

Biotron Publications

Gage, P., G. Ewart, J. Melton and A. Premkumar (2005). Virus Ion Channels Formed by Vpu of HIV-1, the 6K Protein of Alphaviruses and NB of Influenza B Virus. Viral Membrane Proteins: Structure, Function and Drug Design. W. Fischer. New York, Kluwer Academic / Plenum Publishers : Chapter 15.

Ewart, G.D., N. Nasr, H. Naif, G.B. Cox, A.L. Cunningham, and P.W. Gage (2004). Potential new anti-Human Immunodeficiency Virus Type 1compounds depress virus replication in cultured human macrophages. Antimicrobial Agents and Chemotherapy , 48 (6): 2325–2330.

Premkumar, A., G. D. Ewart, G. B. Cox and P. W. Gage (2004). An amino-acid substitution in the influenza-B NB protein affects ion-channel gating. J Membr Biol 197( 3): 135-43.

Premkumar, A., L Wilson, G.D. Ewart, and P.W. Gage (2004). Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride. FEBS Letters 557: 99-103).

Wilson, L, Mckinlay C, Gage P, Ewart,G (2004). SARS coronavirus E protein forms cation-selective ion channels. Virology 330: 322–331.

Ewart, G.D., K. Mills, G.B. Cox, and P.W. Gage (2002). Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu. Eur Biophys J . 31(1): 26-35.

Melton, J.V., G.D. Ewart, R.C. Weir, P.G. Board, E. Lee, and P.W. Gage (2002). Alphavirus 6K proteins form ion channels. J Biol Chem . 277(49): 46923-31.

Ewart, GD., Greber, D., Cox, GB. and Gage, PW (1999). Ion Channels Formed By Vpu, An HIV-1-Encoded Protein (A Potential Target For AIDS Therapeutic Drugs?). Australian Biochemist 30(3): 11-13.

Ewart, G.D., Sutherland, T., Gage, P.W. and Cox, G.B. (1996). The Vpu protein of human immunodeficiency virus type-1 forms cation-selective ion channels. J. Virol. 70(10): 7108-7115.

Other Virion-Related Publications

Bour, S., Strebel, K., (2003). The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes Infect . 5, 1029–1039.

Park, S. H., A. A. Morse, A. A. Nevzorov, M. F. Mesleh, M. Oblatt-Montal, M. Montal, and S. J. Opella. (2003). Three-dimensional structure of the channel-forming trans-membrane domain of virus protein u (Vpu) from HIV-1. J. Mol. Biol. 333:409–424.

Muscion

Dulhunty AF, Cengia L, Young J, Pace SM, Harvey PJ, Lamb GD, Chan YN, Wimmer N, Toth I, Casarotto MG. (2005) Functional implications of modifying RyR-activating peptides for membrane permeability. Br J Pharmacol. 144(6):743-54.

Board, P.G., Coggan, M., Watson, S., Gage, P.W., and Dulhunty, A.F. (2004) CLIC-2 modulates cardiac ryanodine receptor Ca(2+) release channels. The International Journal of Biochemistry & Cell Biology 36, 1599-1612.

Dulhunty AF, Curtis SM, Watson S, Cengia L, Casarotto MG. (2004) Multiple actions of imperatoxin A on ryanodine receptors: interactions with the II-III loop "A" fragment. J Biol Chem. 19;279(12):11853-62. Epub 2003 Dec 29.

Dulhunty AF, Curtis SM, Cengia L, Sakowska M, Casarotto MG. (2004) Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release. Biochem J. 379 (Pt 1):161-72.

Dulhunty, A.,, Gage, P., Curtis, S., Chelvanayagam, G. and Board, P. (2001). The Glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator. Journal of Biological Chemistry 276, 3319-3323.

 

PRODUCT DEVELOPMENT

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